Jo-Ann Guion, 72, died in her home on March 21, 2018 in St. Louis, MO due to complications from pancreatic cancer. She was a devoted and loving mother and wife. Mrs. Guion is survived by her husband, Robert Guion, son, John Anthony Gertken III (Mary), daughter, Vicki Gertken-Tunstall (Dan), son, Christopher Louis Gertken(Elisa), brother, Dale Lay(Joyce). She is also survived by 7 grandchildren (Elisa, Byron, Chrissy, Michael, Thomas, Allison & Jake), 12 great grandchildren (Michael, Krystella, Elizabeth, Zachary, Hannah, Leila, Devin, Gabriel, Joshua, Daniel, Zelda, Dominick, 2 great-great grandchildren (Anessia, Julian) She is preceded in death by her first husband of 41 years, (John Anthony Gertken Jr.), Father (Louis C. Lay), Mother (Gertrude Lay) In lieu of flowers, please donate to the BJC Foundation for Hospice.